EMBO Press

BACE1 regulates sleep–wake cycle through both enzymatic and non–enzymatic actions

A proteolytically inactive BACE1 knock-in (BACE1-KI, D289N) is compared with a BACE1 knockout (BACE1-KO) mouse to dissect ...
eLife

Increased layer 5 Martinotti cell excitation reduces pyramidal cell population plasticity and improves learned motor execution

This valuable study addresses a critical and timely question regarding the role of a subpopulation of cortical interneurons (Chrna2-expressing Martinotti cells) in motor learning and cortical dynamics ...