Frontiers

Application and prospects of genetic engineering in CAR-NK cell therapy

With the rapid advancement of genetic engineering technologies, CAR-NK cell therapy, as an emerging immunotherapeutic approach, has demonstrated significant potential. CAR-NK cells recognize and ...
GitHub

Unsupervised, Label-Agnostic Feature Selection for Biomedical Data

This work presents a novel, label-agnostic, multi-objective feature selection framework for high-dimensional biomedical data. The method jointly optimizes two intrinsic properties: distributional ...
GEN

Industry-Academia Collaboration Formed to Improve Cell and Gene Therapy Manufacturing

Bracco Imaging and Limula, a life science tools company specializing in automated cell and gene therapy manufacturing solutions, launched a R&D project in collaboration with Nicola Vannini, PhD, who ...
BioSpace

selectION Demonstrates Safety and Disease-Modifying Mechanism of Action of its Investigational Drug, si-544, in Phase 1b Proof-of-Concept Trial in Psoriasis, a T Cell-Mediated ...

· si-544 is the first highly potent and selective Kv1.3 blocker to safely achieve patient plasma levels suitable for high target engagement · Excellent safety and tolerability consistent with prior ...
Phys.org

DNA folding more important for cell function than previously thought

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.
The Verge

Microsoft Excel adds Copilot AI to help fill in spreadsheet cells

The new ‘COPILOT’ function uses AI to generate summaries, tags, tables, and more based on a group of cells. The new ‘COPILOT’ function uses AI to generate summaries, tags, tables, and more based on a ...
Medscape

HHS Launches Ambitious Stem Cell Program to Restore Brain Function

The federal government is looking for researchers who can, in 5 years, develop stem cell treatments to repair brain damage caused by stroke, neurodegeneration, and trauma. The Functional Repair of ...
IEEE

Learning-Based Joint Antenna Selection and Precoding Design for Cell-Free MIMO Networks

Abstract: This paper considers a downlink cell-free multiple-input multiple-output (MIMO) network in which multiple multi-antenna access points (APs) serve multiple users via coherent joint ...
Frontiers

Langerhans cells drive Tfh and B cell responses independent of canonical cytokine signals

Dendritic cells (DCs) are key regulators of adaptive immunity, guiding T helper (Th) cell differentiation through antigen presentation, co-stimulation, and cytokine production. However, in ...
ascopubs.org

Quantitative Multiplex Immunofluorescence Assay for Trophoblast Cell-Surface Antigen 2 and Human Epidermal Growth Factor Receptor 2 Expression in Breast Cancer: Toward Guiding ...

Phase II Trial of TAS-102 in Colorectal Cancer Patients With Circulating Tumor DNA-Defined Minimal Residual Disease After Adjuvant Therapy: INTERCEPT-TT A multiplex QIF assay was optimized on tissue ...
Healio

Zimislecel, a novel cell therapy, appears to restore islet function in type 1 diabetes

Please provide your email address to receive an email when new articles are posted on . Zimislecel is an investigational stem cell-derived islet therapy for type 1 diabetes. Ten of 12 participants no ...