PURPOSE: E-cadherin (E-cad) and its associated intracellular molecules, catenins, are critical for intercellular epithelial adhesion and are often expressed in non–small-cell lung carcinomas (NSCLCs).

A Singaporean research team has developed CAN-Scan (short for Cancer Scan), a next-generation precision oncology platform ...

Autoimmune diseases that stem from an autoaggression of the immune system toward a subject's own tissues and organs still represent a field of intense research in the hope to identify why this occurs ...

The field of cancer research has increasingly focused on the intricate interplay between regulated cell death (RCD) pathways and the immune microenvironment in tumor progression and treatment.

A multi-disciplinary approach was employed, using a combination of multiomic techniques, including single-cell RNA-sequencing ...

For biologists, DNA microarrays present at once unprecedented opportunities and monumental challenges. In the opportunities column, microarrays produce genome-wide gene expression snapshots, ...

Northwestern Medicine scientists have discovered how a specific transcription factor promotes genetic reprogramming and chemotherapy resistance in ovarian cancer cells, findings that may inform new ...

Pancreatic cancer is the fifth leading cause of death in the United States with approximately 28,000 deaths/year. Notwithstanding all the efforts, it is still one of the most difficult cancers to ...