Novel annotated Patient-Derived tumor Xenografts (PDX) propagated in immunodeficient mice and Organoids (PDO) in Matrigel have become essential models to study inter- and intra-tumor heterogeneity, ...
Spheroids and organoids, two examples of 3D cell culture models, have become invaluable tools to study the processes that dictate behavior of tissues under physiological and pathological conditions, ...