Alzheimer's disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a ...

RNA interference using small interfering RNAs (siRNAs) has become a mainstay of functional gene characterization and has ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

The Tas protein uses an RNA guide to recognize a specific target DNA sequence. A vast search of natural diversity has led scientists at MIT’s McGovern Institute and the Broad Institute of MIT and ...

Scientists have transformed RNA, a biological molecule present in all living cells, into a biosensor that can detect tiny chemicals relevant to human health. Research by scientists centers on RNA, a ...

Even without deep computational skills, scientists can use the CRISPRware program to quickly browse entire libraries of precomputed guide RNAs for six model organisms, zoom in on their gene or region ...

The sperm is not a passive supplier of genetic material to the egg. A study from Linköping University, Sweden, shows that ...

A groundbreaking study reveals that human cells initiate self-destruction processes when viruses disrupt RNA production, offering new insights into innate antiviral defenses. Conducted and reported on ...

Our immune systems function by employing two separate responses when in contact with disease. The first is the innate immune system, which aids in monitoring for infection throughout the body. Innate ...

How do stem cells know what to become? Nearly three decades after scientists isolated the first human embryonic stem cells, ...