This Focus brings together a selection of Reviews, Perspectives and related research that integrate the most recent advances in our understanding of how the brain controls energy homeostasis. This is ...

Well-being requires the maintenance of energy stores, water, and sodium within permissive zones. The brain, as ringleader, orchestrates their homeostatic control. It senses disturbances, decides what ...

Fat mass development and obesity have been associated with inappropriate food intake behaviors. Food intake is regulated by homeostatic and non-homeostatic control systems, as well as gut ...