BMJ Open

Comparative effectiveness of opioid versus opioid-free analgesia after outpatient breast surgery: PAIN-Alt trial protocol

Introduction Excessive opioid prescribing after surgery can lead to adverse events and exacerbate the opioid crisis. Patients undergoing outpatient breast surgery are often prescribed opioids to ...
RMD Open

High-intensity interval and resistance training programme improves pain and fatigue outcomes in people with systemic sclerosis: a European multicentre ra…

Background Pain and fatigue are among the most debilitating symptoms of systemic sclerosis (SSc), severely impairing quality ...
BMJ

Human Albumin infusion in liver Cirrhosis and overt Hepatic Encephalopathy (HACHE): protocol of an investigator-initiated, open-label, multicentre, randomised controlled trial

Sample size is estimated by using significant difference test in the proportion between two groups on the PASS software V.15.0.5. Notably, until now, there are no data regarding the difference in the ...
Journal of Epidemiology and Community Health (JECH)

Effects of a whole-school relationships and sexual health intervention on non-competent sexual debut: cluster-randomised trial

Background Relationships and sex education (RSE) impacts some sexual behaviours but could be strengthened by incorporating ...