Explore this issue of The New England Journal of Medicine (Vol. 374 No. 13).

The two academic authors of the article by Jayne et al., Avacopan for the Treatment of ANCA-Associated Vasculitis, N Engl J Med 2021;384:599-609, 1 request retraction of the article because, according ...

To the Editor: At the time of the publication of the first PREDIMED (Prevención con Dieta Mediterránea) trial results in 2013, 1 the relative reduction of 30% in the risk of cardiovascular events ...

Many patients with transplanted kidneys ultimately lose them because of antibody-mediated rejection, yet approved therapies are lacking. Multiple mechanisms appear to be involved, beginning with donor ...

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 21).

A 30-year-old man with aplastic anemia presented with fever, nonpruritic rash, and ankle and knee pain. Ten days before presentation, he had completed a course of horse antithymocyte globulin.

To the Editor: In the phase 3 GRADUATE trials of gantenerumab for early Alzheimer’s disease reported by Bateman et al. (Nov. 16 issue), 1 participants receiving gantenerumab had a greater decrease in ...

The Pediatric Research Equity Act was intended to promote the development and testing of prescription drugs for children. But its implementation has been constrained.

A 56-year-old woman was hospitalized with gait instability. Eight weeks earlier, she had noticed ascending symmetric sensations of painful “pins and needles” that had begun in her feet; she later ...

Orforglipron, a small-molecule, nonpeptide oral glucagon-like peptide-1 (GLP-1) receptor agonist, is being investigated as a treatment for obesity.In this phase 3, multinational, randomized, double ...

Current curative-intent management of high-risk localized prostate cancer (nonmetastatic prostate cancer with extraprostatic extension or seminal-vesicle invasion, a histologic Gleason score of ≥8 [on ...

Although medications with glucagon-like peptide-1 (GLP-1) receptor agonist activity have transformed the management of obesity and shown substantial cardiometabolic benefits, unmet needs remain.