A newly developed mouse model enables real-time visualization of RNA Polymerase II (RNAP2) during DNA transcription, as ...

Michael Buck, PhD, professor of biochemistry in the Jacobs School, recently received NIH funding to explore how molecular readers of DNA access and activate seemingly hidden genes.

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a ...

Every cell in the body has the same DNA, but different cell types—such as muscle or brain cells—use different parts of it.

Researchers discovered that embryos must clear maternal mRNAs to develop properly. When cleanup fails, it causes aberrant ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...