According to “Global Cancer Statistics- 2022”, colorectal cancer (CRC) ranks third in incidence and second in cancer-related ...

DJ-1 is a protein with wide subcellular distribution and pleiotropic functions. The loss-of-function mutations of DJ-1 are associated with autosomal recessive early-onset Parkinson's disease yet the ...

Misfolded proteins cause intracellular stress, which induces the unfolded-protein response (UPR). The UPR is a three-pronged signalling pathway that induces genes which cause cells to acquire a ...

The endoplasmic reticulum (ER) is a compartment (organelle) in eukaryotic cells that consists of membrane sacs called cisternae. Because of the bound ribosomes, the 'rough' ER is the site of synthesis ...

Paul Victor, Dhamodharan Umapathy, Leema George, Udyama Juttada, Goutham V. Ganesh, Karan Naresh Amin, Vijay Viswanathan and Kunka Mohanram Ramkumar Increasing evidence in substantiating the roles of ...

A single 6-hr exposure to vinyl chloride monomer (5%) produces extensive vacuolization of centrolobular liver parenchyma and focal midzonal necrosis in the hepatic lobuole in phenobarbital-pretreated ...