As flu season approaches and public health officials roll out their annual push for vaccination, Allen Institute scientists are learning why vaccines can trigger a weaker response in older adults, ...

By profiling over 16 million immune cells from people aged 22 to 65 after flu vaccination, scientists discovered that memory T cell function changes with age.

The regulatory division of the immune system is vital for its overall function. Immune T cells originate in the bone marrow and then travel to the thymus—a kind of biological police academy. 2 Here, ...

The first patient has been dosed in a Phase 1 trial testing the experimental CAR T-cell therapy obecabtagene autoleucel for progressive MS.

Urolithin A, a natural postbiotic known to trigger mitophagy, rejuvenated key immune cell functions in healthy middle-aged ...

CAR T-cell therapy was first developed as a lymphoma treatment but has recently been applied to autoimmune diseases, primarily lupus, systemic sclerosis, and myositis. Up to this point, ulcerative ...

Scientists have found a way to transform hard-to-treat tumors into targets for the immune system. Using two protein stimulators, they activated strong T-cell and B-cell responses and built immune ...

Cabaletta Bio’s CAR-T cell therapy has eliminated the overreactive B cells of two patients with an autoimmune disease without preconditioning chemotherapy, pleasing investors and analysts while ...