When neuroscientists analyzed the exact properties of nerve connections in the brain, they made a startling observation: At a key connection, or synapse, messages are sent against the usual stream of ...

Recent technological advances have opened new possibilities for neuroscience research, allowing researchers to map the ...

(1) A nerve impulse arrives. (2) This causes calcium ion channels to open, resulting in an influx of calcium ions in the terminal. (3) This causes synaptic vesicles to fuse with the terminal membrane, ...

Parkinson’s and Alzheimer’s diseases are the two most common neurodegenerative disorders, affecting millions of people ...

The synaptotagmin protein family has been studied by neuroscientists for decades. However, most isoforms lack well-defined functions. Now, researchers have identified a crucial, presynaptic role for ...

How do people think, feel, remember, and move? These processes rely on synaptic transmission, where chemical signals are passed between nerve cells using molecular structures called vesicles.

Physiological functioning and homeostasis of the brain rely on finely tuned synaptic transmission, which involves nanoscale alignment between presynaptic neurotransmitter-release machinery and ...

Boost Neuroscience is a “stealth” biotech company that has developed a proprietary synapse network platform based on the work of Nobel Laureate Dr. Thomas Südhof, M.D. Boost was spun out of Stanford ...

Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severely warps their native structure. The true ultrastructure of cells can be ...