Sequence alignment algorithms form the foundation of comparative genomics, structural biology and evolutionary studies by identifying regions of similarity among nucleotide or protein sequences.

Open-access databases such as the European Nucleotide Archive (ENA) contain more than 2.4 million bacterial genomes, and this number continues to grow rapidly. Until now, searching these vast ...

De Bruijn sequences are cyclic strings of length k^n over an alphabet of size k in which every possible substring of length n appears exactly once. Their generation has become a cornerstone of ...

Overview: An algorithm is a step-by-step set of instructions that takes an input and produces a clear output, just like a ...