Researchers can transfect other types of RNA molecules as well. Messenger RNA transfection enables direct analyses of RNA function because the transfected messages can be expressed in the absence of ...

The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi pathway. When miRNA acts as the guide for RNAi, only a ...

The most familiar role for RNA is as a relatively passive intermediary in the translation of information from genes into proteins. But other functions for this versatile molecule have been emerging.

Researchers from the Colour and Food Quality group at the Faculty of Pharmacy (University of Seville), in collaboration with Dr. Marina Ezcurra's group at the University of Kent (UK), have shown that ...

RNA interference (RNAi) offers a fast and easy system to study gene functions. However, the traditionally used small interfering RNAs (siRNAs) can exhibit pronounced and problematic off-target effects ...

RNA interference – RNAi – functions specifically to silence, or deactivate, genes. Among other applications, it promises to be groundbreaking as a way to treat infections of bees by a commercially ...

Using RNA to interfere with a gene’s expression of disease-causing proteins is a validated therapeutic approach, but so far, the products in this drug class only address liver proteins. Reducing ...

New research shows that parasitic nematodes, responsible for infecting more than a billion people globally, carry viruses that may solve the puzzle of why some cause serious diseases. New research ...