The octanol/water partition coefficient P (logP) is a hydrophobicity index and is one of the determining factors for the pharmacokinetics of orally administered substances because it influences ...

Countercurrent chromatography systems were tested and combined to optimize their capacity for handling non-polar and polar substances. Countercurrent chromatography, while an effective method for ...

Partition coefficient (P) is a measure of the relative solubility of a compound in two immiscible solvents, typically being water and an organic solvent. It is useful in evaluating the hydrophobicity ...

An efficient solvent system screening approach that streamlines fractionation of compounds with similar UV absorption eliminates the need for individual partition coefficient calculations, and coupled ...

The aim of this study was to develop a method based upon electrokinetic chromatography (EKC) using oppositely charged surfactant vesicles as a buffer modifier to estimate hydrophobicity (log P) for a ...

In elution mode, separation is based solely on the partitioning of compounds between the mobile and stationary phases. As long as the solute concentrations in the column remain low, the partition ...

In the next decade, the global legal cannabis industry is expected to skyrocket from $10 billion to $57 billion. The pharmaceutical industry is embracing this rapid growth because of the wide range of ...

iMoleQ is a Cloud-based web application designed to predict molecular properties. The development of version 1.0 is currently in progress. The app is built upon our patented research, which utilizes ...

ABSTRACT: Isothermal titration calorimetry (ITC) was applied to investigate the interaction of drugs with liposomes. Two types of titration are possible. One type is when the liposome suspension in ...