SAN DIEGO – All multiple sclerosis patients taking natalizumab (Tysabri) who were diagnosed with progressive multifocal leukoencephalopathy (PML) before symptoms appeared were still alive a year later ...

Although the survival rate of natalizumab-associated progressive multifocal leukoencephalopathy (PML) is better than PML in HIV patients, long-term they may need some assistance and care, Ralf Gold, ...

Figure 1: Pml-/-mice have accelerated revascularization in response to ischaemia. Figure 2: Pml controls Hif-1α activity and accumulation rate in hypoxic conditions. To exclude further that PML ...

A differential blood count revealed grade 3 lymphocytopenia (Figure 1, and Tables S1 and S2 in the Supplementary Appendix). Retrospective analysis revealed that the lymphocytopenia had reached grade 3 ...

Two articles shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, highlight both the challenges and opportunities of genetic approaches to cancer ...

c-myc is a well-known proto-oncogene encoding for a transcription factor that needs to be tightly regulated in order to preserve cell homeostasis. The Promyelocytic Leukaemia gene product PML plays an ...