The human brain is a highly complex structure, and its normal development and functioning is critically dependent on the proper and tightly regulated activity of a large number of genes. Indeed, ...

"The use of genomic microarrays was shown to be useful in the included study population for providing prognostic information regarding time to first treatment. This technique could, with extensive ...

A novel application of microarray technology, where up to 30,000 whole genomes are printed on a single slide, is described in the journal BMC Microbiology this week. The 'Library on a Slide' will help ...

We live in an age in which whole-genome sequences are commonplace on our hard drives and on other storage media and servers throughout the Internet. It is easy to think of a genome in purely digital ...

The human genome project was undertaken to determine the human DNA sequence and analyze variation among individuals. To make use of this information, tools were developed that could collect and ...

Microarrays have been a mainstay of the scientific research community for nearly a decade but given the more stringent demands for accuracy and reliability, have not been as closely embraced in the ...

The Division of Genomic and Molecular Pathology at the University Hospitals Cleveland Medical Center (UHCMC) and Case Western Reserve University (CWRU) School of Medicine is a specialized academic ...

A single genetic test could potentially replace the current two-step approach to diagnosing rare developmental disorders in children. This shift could enable earlier diagnoses for families and save ...

Impact of BRCA1 gene alterations on tumor characteristics and clinical outcome in ovarian cancer (OC) patients. Background: Advanced ovarian clear cell carcinomas (OCCCs) are notoriously drug ...

Pregnancy loss may occur in as many as 25% of all pregnancies. Most of these losses occur in the first trimester, and about ...