Potential autoimmune diseases therapies that target dendritic cells aim to either inhibit immunogenic dendritic cell functions or support their tolerogenic potential (Figure 2). Most strategies ...

Dendritic cells (DCs) are exceptionally potent antigen-presenting cells (APCs) in the human body and are considered the “sentinels” of the immune system. They are essential in establishing, ...

The responsibility of the immune system protects the human body from infections and diseases. This system is made of two separate responses that occur sequentially. The first or innate immune system ...

Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat ...

Importantly, the scientists discovered how high sugar levels in diabetic mice disrupt the normal function of lung dendritic cells during infection. Altered sugar metabolism in these cells led to the ...

Epigenetics is the study of how our cells alter their function by modifying gene expression in our genetic code or deoxyribonucleic acid (DNA). In our cells, DNA is constantly being used to generate ...

AI-driven early detection, personalized therapies, and immune-rejuvenating T-cell engineering promise transformative, durable ...

A Czech scientist has contributed to understanding the function of the thymus—the training center of the immune system. T lymphocytes, key defensive cells, learn in the thymus not to mistake the ...

Immunotherapy uses a person's own immune system to fight cancer. Immune checkpoint inhibitors are one class of immunotherapy that block specific proteins from slowing the immune response. As a result, ...