Cancer’s strongest gene switches push DNA into damaging overdrive, creating repeated breaks and repairs that may fuel tumor ...

Stanford Medicine researchers have built CRISPR-GPT, a large language model designed to automate the full arc of gene-editing ...

A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

A protein found in bowhead whales, one of the longest-living mammals on Earth, could help improve how human cells repair DNA, according to new research from scientists at the Albert Einstein College ...

Transcription factor IIH, or TFIIH, pronounced "TF two H," is a veritable workhorse among the protein complexes that control human cell activity. It plays critical roles both in transcription—the ...

Researchers have discovered how the protein XPD detects severe DNA damage and controls its repair. The XPD protein is a central component of our body's own "DNA repair team," known as nucleotide ...

A protein, TDP43, previously linked to dementia and ALS, has been found to control DNA repair. Researchers say abnormal ...

Scientists discover ALS protein that links DNA repair to cancer and dementia: Study ...