Characterizing the binding sites of monoclonal antibodies (mAbs) on target antigens, their epitopes, can aid in the discovery and development of new therapeutics, diagnostics, and vaccines. For ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

The researchers imaged the antibody-stabilized protein complex using low-temperature electron microscopy. With the help of advanced image-analysis software, the researchers were able to generate an ...

Researchers understand the structure of brains and have mapped them out in some detail, but they still don't know exactly how they process data — for that, a detailed "circuit map" of the brain is ...

Zoonotic diseases jump species to infect humans, and scientists have been studying this transmission chain for many years. Researchers in Austria aimed to perform a comprehensive analysis of the ...

The Collaborative Cross (CC) mouse resource has emerged as an indispensable platform for elucidating the genetic basis of complex traits. By combining high levels of genetic diversity from eight ...

A comprehensive study mapped the dynamic glycosylation landscape of rat serum proteins, uncovering sex- and time-dependent ...