Discovery of a new cancer cell type could enable testing to predict treatment-resistant blood cancer in children with a certain type of leukaemia. This could allow them to reduce treatment intensity ...

A new type of cancer cell that "warrants urgent investigation" has been discovered in childhood leukemia and could impact ...

T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

In a groundbreaking development for cancer treatment, Caribou Biosciences announced promising results from its off-the-shelf CAR-T therapy in patients with advanced B-cell lymphoma. This innovative ...

Researchers from the School of Veterinary Medicine and Perelman School of Medicine have found that YY1 knockout pro-B cells can generate T lineage cells helping B cells produce antibodies. Development ...

Chimeric antigen receptor (CAR) T-cell therapies have transformed cancer and autoimmune disease treatment. Modified CAR proteins equip T cells with the ability to identify and eliminate cancer cells ...