A so-called "molecular chaperone", the protein Hsp70, carries out more functions in the maturation of proteins than previously thought. As the researchers have discovered, Hsp70 not only acts as a ...

Bonn, January 10, 2023 - Scientists led by Prof. Thomas Becker, Director of the Institute of Biochemistry and Molecular Biology at the University Hospital Bonn (UKB), have gained new insights into the ...

Scientists have solved the structure of mitochondrial ATP synthase, an enzyme that makes ATP, adenosine triphosphate, the major energy source of cells. A team of scientists headed by Rosalind Franklin ...

Mitochondrial dysfunction, including decreased mitochondrial respiration and increased mitochondrial stress, is associated with many major human diseases and casual to many pathological defects.

F1FO-ATP synthase is critical for mitochondrial functions. The deregulation of this enzyme results in dampened mitochondrial oxidative phosphorylation (OXPHOS) and activated mitochondrial permeability ...

A team of scientists headed by Rosalind Franklin University Professor David M. Mueller, PhD, has solved the structure of mitochondrial ATP synthase, an enzyme that makes ATP, adenosine triphosphate, ...

The mitochondrial adenosine triphosphate (ATP) synthase produces most of the ATP required by mammalian cells. We isolated porcine tetrameric ATP synthase and solved its structure at 6.2-angstrom ...

Plant Physiology, Vol. 113, No. 1 (Jan., 1997), pp. 191-199 (9 pages) Nucleotide metabolism in potato (Solanum tuberosum) mitochondria was studied using 31P-nuclear magnetic resonance spectroscopy and ...