Spheroids and organoids, two examples of 3D cell culture models, have become invaluable tools to study the processes that dictate behavior of tissues under physiological and pathological conditions, ...

The Advanced Cell Engineering and 3D Models (ACE-3M) Core provides established services offered previously by AIM and C-BASS cores plus new expanded capabilities for tumor organoids grown in 3D ...

Advanced 3D cell models recreate the complexity of human tissues, enabling researchers to examine tumor progression, probe neurological disorders, and assess therapeutic candidates. By capturing the ...

Article reviewed by Julía Crispim da Fontoura, a PhD candidate at the Federal University of Health Sciences of Porto Alegre, Brazil who uses organoids to study drug resistance. Stay up to date on the ...

In the new study, the team used the model to demonstrate that as Alzheimer's pathology accumulates in the brain, specific types of immune cells called CT8+ T Cells surge into the brain and amplify the ...

How do embryos develop? Why does the cortex of the mammalian brain fold? How do we feel touch at our fingertips? These and ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

A groundbreaking study reveals how neurons sense and transmit mechanical forces across their membranes—a key to understanding touch, movement, and development.

Neuronal death is the indisputable endgame of Alzheimer’s disease, but what does the killing, and how? To try to solve the mystery, researchers have staged increasingly complex crime scenes in ...